OR51F2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51F2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51F2-associated genes across cancer lineages are OR10A6, CFHR2, and LRRC31. Each is linked with OR51F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51F2-to-partner and partner-to-OR51F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A6 grouped by OR51F2-low versus OR51F2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51F2→partner) and Y-score (partner→OR51F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR10A6 →+0.044+5.201<.001.00631
BLOOD_LeukemiaCFHR2 →+0.395+5.539<.001.00331
SKINLRRC31 →+0.023+3.415<.001.00431
SKINSNTN →+0.034+3.196.002.00731
CNSRETNLB →+0.338+5.321<.001.00531
CNSOR10D3 →+0.046+5.321<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OR10A6 by OR51F2 expression — BLOOD_Leukemia

Box plot of OR10A6 in OR51F2-low vs OR51F2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration