OR51F1

Across TCGA patient cohorts, OR51F1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51F1-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, STAT3_pY705, and HER3. Each is linked with OR51F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51F1-to-partner and partner-to-OR51F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by OR51F1-low versus OR51F1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51F1→partner) and Y-score (partner→OR51F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.746	+3.459	.001	.004	3	2
UCEC	STAT3_pY705 →	-0.514	-3.000	<.001	.037	3	1
SKCM	HER3 →	+0.445	+3.321	.013	.009	3	1
SKCM	p21 →	-0.396	-2.098	.035	.018	3	1
SKCM	S6_pS235_S236 →	-0.444	-2.807	.015	.003	3	1
UCEC	14-3-3_beta →	-0.154	-2.986	.007	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Acetyl-a-Tubulin-Lys40 by OR51F1 expression — SKCM

Explore this box plot interactively →