OR51F1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51F1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR51F1-associated genes across cancer lineages are OR6C74, KRTAP5-11, and KRTAP29-1. Each is linked with OR51F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51F1-to-partner and partner-to-OR51F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C74 grouped by OR51F1-low versus OR51F1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51F1→partner) and Y-score (partner→OR51F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINOR6C74 →+0.078+4.217<.001.00131
SKINKRTAP5-11 →+0.037+3.684<.001.00631
SKINKRTAP29-1 →+0.020+4.217<.001.00131
SKINIFNA17 →+0.018+3.930<.001.00331
SKINAMY2A →+0.067+3.930<.001.00331
SKINOR1D5 →+0.014+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR6C74 by OR51F1 expression — SKIN

Box plot of OR6C74 in OR51F1-low vs OR51F1-high samples in SKIN.

Explore this box plot interactively →

Exploration