OR51E2

Across TCGA pan-cancer cohorts, OR51E2 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of OR51E2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR51E2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR51E2 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

KIRC, COAD, and BRCA are the cancer types where OR51E2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR51E2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+1.562	<.001	11	view →
COAD	All	II,III,IV	−0.798	.001	6	view →
BRCA	Female	II,III,IV	+0.226	<.001	6	view →
HNSC	Female	All	+0.130	.003	6	view →
LIHC	Female	All	+0.102	<.001	6	view →
LUAD	All	All	+0.089	.004	6	view →
LUSC	All	All	+0.172	.007	4	view →
PRAD	All	All	+3.462	<.001	2	view →
READ	All	All	−1.427	.001	2	view →
UCEC	All	All	−0.733	.010	2	view →
CHOL	All	All	+0.246	.007	2	view →
BLCA	Male	III,IV	−0.408	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

OR51E2–KIRC

Open the KIRC breakdown →