OR51E1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR51E1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OR51E1 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher OR51E1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR51E1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LIHC, SKCM, and UCS are the cancer types where OR51E1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCDFSMedianIII,IV0.0770.414.0049view →
SKCMOSMedianAll1.0000.865.0117view →
UCSOSMedianAll0.1530.687.0196view →
ACCOSMedianAll0.1180.624.0386view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OR51E1–LIHC (DFS)

Kaplan–Meier survival curve for OR51E1 mutant vs wild-type samples in LIHC.

Open the LIHC breakdown →

Exploration