OR51E1

Across TCGA patient cohorts, OR51E1 mutation is significantly associated with the RNA expression of many other genes, with 3,644 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51E1-associated genes across cancer lineages are SNRPD3, AAGAB, and TRIP4. Each is linked with OR51E1 in more than 4 cancer types. Because this analysis shows association rather than direction, both OR51E1-to-partner and partner-to-OR51E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPD3 grouped by OR51E1-low versus OR51E1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51E1→partner) and Y-score (partner→OR51E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPD3 →	+0.365	+3.820	.001	<.001	3	4
UCEC	AAGAB →	+0.563	+2.101	<.001	<.001	3	4
UCEC	TRIP4 →	+0.438	+2.828	<.001	.001	3	4
UCEC	OIP5 →	+0.825	+3.247	<.001	<.001	3	4
UCEC	DHDDS →	+0.317	+2.839	.001	.001	3	4
UCEC	HAT1 →	+0.509	+2.247	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,644 associations by consensus.

SNRPD3 by OR51E1 expression — COAD

Explore this box plot interactively →