OR51E1

Across TCGA patient cohorts, OR51E1 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51E1-associated genes across cancer lineages are Gab2, TFRC, and ATM. Each is linked with OR51E1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51E1-to-partner and partner-to-OR51E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gab2 grouped by OR51E1-low versus OR51E1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51E1→partner) and Y-score (partner→OR51E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Gab2 →	+0.297	+2.321	.014	.033	3	3
UCEC	TFRC →	+0.512	+1.678	.004	.021	3	3
UCEC	ATM →	-0.504	-1.807	.001	.004	3	3
UCEC	c-Jun_pS73 →	-0.124	-1.690	.022	.042	3	3
COAD	Caspase-7-cleavedD198 →	+1.091	+3.338	<.001	.004	3	3
UCEC	EGFR_pY1068 →	-0.300	-3.087	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Gab2 by OR51E1 expression — UCEC

Explore this box plot interactively →