Across TCGA pan-cancer cohorts, OR51D1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR51D1 data layer compared with 9 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher OR51D1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR51D1 expression acts as an unfavorable survival marker.

LUSC, GBM, and LIHC are the cancer types where OR51D1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	II,III,IV	0.215	0.616	.010	24	view →
GBM	OS	Median	All	0.045	0.416	<.001	18	view →
LIHC	OS	Median	All	0.167	0.704	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: OR51D1 tumor-vs-normal RNA expression · all OR51D1 data types