Across TCGA pan-cancer cohorts, OR51C1P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR51C1P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR51C1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR51C1P is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.
KIRC, PRAD, and READ are the cancer types where OR51C1P tumor–normal differential expression is most reproducible.