OR51B6

Across TCGA patient cohorts, OR51B6 mutation is significantly associated with the RNA expression of many other genes, with 1,332 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51B6-associated genes across cancer lineages are RNU6-1213P, RNA5SP461, and ESS2. Each is linked with OR51B6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51B6-to-partner and partner-to-OR51B6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by OR51B6-low versus OR51B6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B6→partner) and Y-score (partner→OR51B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.153	+3.374	<.001	.003	3	3
UCEC	RNA5SP461 →	+0.178	+3.890	<.001	.007	3	2
UCEC	ESS2 →	+0.360	+3.180	<.001	<.001	3	2
SKCM	HIRA →	+0.291	+2.845	.006	.001	3	2
SKCM	ITPK1 →	+0.486	+2.424	.004	.001	3	2
SKCM	TRIB3 →	+0.670	+2.019	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,332 associations by consensus.

RNU6-1213P by OR51B6 expression — UCEC

Explore this box plot interactively →