OR51B6

Across TCGA patient cohorts, OR51B6 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51B6-associated genes across cancer lineages are S6_pS235_S236, S6_pS240_S244, and Cyclin-B1. Each is linked with OR51B6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51B6-to-partner and partner-to-OR51B6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S6_pS235_S236 grouped by OR51B6-low versus OR51B6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B6→partner) and Y-score (partner→OR51B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	S6_pS235_S236 →	+0.364	+2.182	.036	.033	3	2
UCEC	S6_pS240_S244 →	+0.463	+2.321	.007	.034	3	2
SKCM	Cyclin-B1 →	+0.478	+3.321	.004	.009	3	2
UCEC	LKB1 →	-0.109	-3.169	.015	.019	3	2
UCEC	PCNA →	+0.188	+3.321	.040	.010	3	2
UCEC	STAT3_pY705 →	-0.292	-2.321	.008	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

S6_pS235_S236 by OR51B6 expression — SKCM

Explore this box plot interactively →