OR51B4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR51B4 mutation is significantly associated with the RNA expression of many other genes, with 2,742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51B4-associated genes across cancer lineages are TRIM53CP, RNA5SP160, and TRDV2. Each is linked with OR51B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51B4-to-partner and partner-to-OR51B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM53CP grouped by OR51B4-low versus OR51B4-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B4→partner) and Y-score (partner→OR51B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READTRIM53CP →+0.088+5.691<.001<.00133
READRNA5SP160 →+0.627+4.023<.001.00532
READTRDV2 →+0.262+3.626<.001.00932
READMIR4797 →+0.640+4.054<.001.00432
UCECSNX3P1Y →+0.084+4.230<.001.00432
BRCAOR7E149P →+0.041+5.148.002.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,742 associations by consensus.

TRIM53CP by OR51B4 expression — READ

Box plot of TRIM53CP in OR51B4-low vs OR51B4-high samples in READ.

Explore this box plot interactively →

Exploration