OR51B4

Across TCGA patient cohorts, OR51B4 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51B4-associated genes across cancer lineages are Notch1, Acetyl-a-Tubulin-Lys40, and Cyclin-B1. Each is linked with OR51B4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51B4-to-partner and partner-to-OR51B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by OR51B4-low versus OR51B4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B4→partner) and Y-score (partner→OR51B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.189	+3.335	.001	.005	3	3
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.559	+1.874	.013	.049	3	2
UCEC	Cyclin-B1 →	+0.672	+2.321	.003	.006	3	2
UCEC	STAT3_pY705 →	-0.452	-2.115	<.001	.016	3	2
UCEC	TFRC →	+0.634	+2.321	.003	.033	3	2
UCEC	Caspase-7-cleavedD198 →	+0.687	+2.341	.005	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Notch1 by OR51B4 expression — UCEC

Explore this box plot interactively →