OR51B4

Across TCGA cell cohorts, OR51B4 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51B4-associated genes across cancer lineages are RTL4, KRTAP2-2, and SERPINB12. Each is linked with OR51B4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51B4-to-partner and partner-to-OR51B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RTL4 grouped by OR51B4-low versus OR51B4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B4→partner) and Y-score (partner→OR51B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RTL4 →	+0.006	+5.000	<.001	<.001	3	1
SKIN	KRTAP2-2 →	+0.081	+3.930	<.001	.003	3	1
LARGE_INTESTINE	SERPINB12 →	+0.152	+3.823	<.001	.006	3	1
LARGE_INTESTINE	QRFPR →	+0.739	+3.854	.005	.006	3	1
LARGE_INTESTINE	TECRL →	+0.017	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

RTL4 by OR51B4 expression — SKIN

Explore this box plot interactively →