Across TCGA pan-cancer cohorts, OR51B3P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR51B3P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR51B3P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR51B3P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
KIRC and KICH are the cancer types where OR51B3P tumor–normal differential expression is most reproducible.