OR51B2

Across TCGA patient cohorts, OR51B2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible OR51B2-associated genes across cancer lineages are MAK, DPPA2, and TXNDC2. Each is linked with OR51B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51B2-to-partner and partner-to-OR51B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAK grouped by OR51B2-low versus OR51B2-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B2→partner) and Y-score (partner→OR51B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	MAK →	+1.167	+3.930	.003	.005	3	1
SCLC	DPPA2 →	+0.110	+4.169	.001	.003	3	1
SCLC	TXNDC2 →	+0.177	+4.584	.003	.001	3	1
SCLC	OR7G2 →	+0.102	+4.149	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MAK by OR51B2 expression — SCLC

Explore this box plot interactively →