OR51B2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51B2 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR51B2-associated genes across cancer lineages are CPB1, FAM71B, and PGA5. Each is linked with OR51B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51B2-to-partner and partner-to-OR51B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPB1 grouped by OR51B2-low versus OR51B2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B2→partner) and Y-score (partner→OR51B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSCPB1 →+0.272+3.584<.001.00832
LARGE_INTESTINEFAM71B →+0.002+3.700<.001.00932
OESOPHAGUSPGA5 →+0.094+3.584.006.00831
LARGE_INTESTINEGOT1L1 →+0.020+3.700<.001.00931
LARGE_INTESTINELY6L →+0.078+3.700.001.00931
LARGE_INTESTINEOR6Q1 →+0.012+3.700<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

CPB1 by OR51B2 expression — OESOPHAGUS

Box plot of CPB1 in OR51B2-low vs OR51B2-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration