Across TCGA patient cohorts, OR51A4 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51A4-associated genes across cancer lineages are PDCD4, EGFR_pY1068, and eIF4E. Each is linked with OR51A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51A4-to-partner and partner-to-OR51A4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51A4→partner) and Y-score (partner→OR51A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.618	-2.896	<.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.312	-2.087	.001	.005	3	1
UCEC	eIF4E →	+0.194	+2.087	.016	.005	3	1
UCEC	A-Raf_pS299 →	-0.140	-2.222	.002	.010	3	1
UCEC	FoxM1 →	+0.248	+2.584	.012	.001	3	1
UCEC	FOXO3a_pS318_S321 →	-0.094	-1.797	.049	.025	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

OR51A4 survival (RNA) · tumor vs normal (RNA) · all OR51A4 data types