Across TCGA cell cohorts, OR51A4 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51A4-associated genes across cancer lineages are HTR1B, GRM4, and KCNK17. Each is linked with OR51A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51A4-to-partner and partner-to-OR51A4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51A4→partner) and Y-score (partner→OR51A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	HTR1B →	+0.379	+3.514	.005	.008	3	1
LARGE_INTESTINE	GRM4 →	+1.120	+3.491	<.001	.004	3	1
LARGE_INTESTINE	KCNK17 →	+0.075	+3.906	<.001	.002	3	1
LARGE_INTESTINE	NAA11 →	+0.302	+3.443	.009	.009	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR2B2 →	+0.024	+3.669	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

OR51A4 survival (RNA) · tumor vs normal (RNA) · all OR51A4 data types