OR4X1

Across TCGA cell cohorts, OR4X1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible OR4X1-associated genes across cancer lineages are CRYBB1, DHRS7C, and FABP12. Each is linked with OR4X1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4X1-to-partner and partner-to-OR4X1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by OR4X1-low versus OR4X1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4X1→partner) and Y-score (partner→OR4X1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CRYBB1 →	+0.022	+5.000	<.001	.006	3	1
PANCREAS	DHRS7C →	+0.075	+5.000	<.001	.006	3	1
SOFT_TISSUE	FABP12 →	+0.076	+4.169	.003	.002	3	1
SKIN	GPR119 →	+0.018	+3.196	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CRYBB1 by OR4X1 expression — PANCREAS

Explore this box plot interactively →