OR4S2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR4S2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OR4S2-associated genes across cancer lineages are LIPK and OR10G2. Each is linked with OR4S2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4S2-to-partner and partner-to-OR4S2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIPK grouped by OR4S2-low versus OR4S2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4S2→partner) and Y-score (partner→OR4S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUELIPK →+0.032+4.930<.001.00831
SKINOR10G2 →+0.023+6.022<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LIPK by OR4S2 expression — SOFT_TISSUE

Box plot of LIPK in OR4S2-low vs OR4S2-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration