OR4P4

Across TCGA pan-cancer cohorts, OR4P4 Mutation is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated OR4P4 data layer compared with 4 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OR4P4 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated OR4P4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, ESCA, and COAD are the cancer types where OR4P4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.828	.012	32	view →
ESCA	OS	Median	II,III,IV	0.103	0.868	<.001	18	view →
COAD	OS	Median	II,III,IV	0.001	0.860	<.001	6	view →
SCLC	OS	Median	All	0.082	0.653	.002	6	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →
SKCM	DFS	Median	IV	1.000	0.201	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR4P4–UCEC (DFS)

Open the UCEC breakdown →