Across TCGA pan-cancer cohorts, OR4N5 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OR4N5 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher OR4N5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4N5 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

CESC, COAD, and HNSC are the cancer types where OR4N5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.279	0.801	<.001	42	view →
COAD	OS	Median	All	0.140	0.806	<.001	24	view →
HNSC	OS	Median	II,III,IV	0.174	0.743	.002	21	view →
ESCA	OS	Median	All	0.211	0.700	.020	9	view →
SKCM	DFS	Median	II,III,IV	0.690	0.275	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: OR4N5 tumor-vs-normal RNA expression · all OR4N5 data types