OR4N5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR4N5 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4N5-associated genes across cancer lineages are Smad4, Tuberin, and VHL. Each is linked with OR4N5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4N5-to-partner and partner-to-OR4N5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4N5→partner) and Y-score (partner→OR4N5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSmad4 →-0.140-3.000.045.03732
UCECTuberin →+0.312+2.817.045.03632
SKCMVHL →-0.638-2.584.009.00932
LUAD14-3-3_beta →-0.197-2.983.007.03631
LUADGSK-3_pS9 →+0.427+3.000.042.03631
LUADPR →-0.172-2.966.032.03631
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

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