OR4M2

Across TCGA patient cohorts, OR4M2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible OR4M2-associated genes across cancer lineages are CDH16 and HTR3D. Each is linked with OR4M2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4M2-to-partner and partner-to-OR4M2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDH16 grouped by OR4M2-low versus OR4M2-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4M2→partner) and Y-score (partner→OR4M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	CDH16 →	+1.552	+6.228	<.001	.001	3	1
SCLC	HTR3D →	+0.101	+5.189	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CDH16 by OR4M2 expression — SCLC

Explore this box plot interactively →