OR4M2

Across TCGA cell cohorts, OR4M2 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4M2-associated genes across cancer lineages are SKOR2, PRAMEF4, and DRD3. Each is linked with OR4M2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4M2-to-partner and partner-to-OR4M2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKOR2 grouped by OR4M2-low versus OR4M2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4M2→partner) and Y-score (partner→OR4M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SKOR2 →	+0.023	+5.285	<.001	.003	3	1
STOMACH	PRAMEF4 →	+0.006	+5.285	<.001	.003	3	1
BLOOD_Leukemia	DRD3 →	+0.012	+5.201	<.001	.006	3	1
BLOOD_Leukemia	KRTAP3-3 →	+0.043	+6.569	<.001	<.001	3	1
LUNG_SCLC	NUP210L →	+0.095	+3.724	.008	.001	3	1
LUNG_SCLC	DHRS7C →	+0.716	+2.938	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

SKOR2 by OR4M2 expression — STOMACH

Explore this box plot interactively →