OR4L1

Across TCGA cell cohorts, OR4L1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4L1-associated genes across cancer lineages are FAM71A, WSCD2, and LILRA5. Each is linked with OR4L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4L1-to-partner and partner-to-OR4L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM71A grouped by OR4L1-low versus OR4L1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4L1→partner) and Y-score (partner→OR4L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM71A →	+0.080	+3.453	<.001	.009	3	1
LARGE_INTESTINE	WSCD2 →	+0.145	+3.660	<.001	.005	3	1
LUNG_NSCLC_LUAD	LILRA5 →	+0.038	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	LCE2C →	+0.031	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FAM71A by OR4L1 expression — LARGE_INTESTINE

Explore this box plot interactively →