OR4K4P

Across TCGA pan-cancer cohorts, OR4K4P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated OR4K4P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OR4K4P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR4K4P expression acts as an unfavorable survival marker, although some lineages such as GBM and LGG show a favorable association.

ACC, STAD, and ESCA are the cancer types where OR4K4P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.145	0.888	<.001	135	view →
STAD	DFS	Tertile	IV	0.068	0.480	<.001	72	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
UCEC	OS	Tertile	All	0.836	0.928	.005	36	view →
BLCA	DFS	Tertile	All	0.249	0.627	.044	18	view →
GBM	DFS	Tertile	All	0.458	0.183	.011	18	view →
KIRP	DFS	Tertile	II,III,IV	0.157	0.686	.031	18	view →
MESO	DFS	Tertile	III,IV	0.099	0.414	.035	9	view →
LIHC	DFS	Tertile	All	0.014	0.527	<.001	9	view →
LGG	OS	Tertile	All	0.955	0.859	.004	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

OR4K4P–ACC (OS)

Open the ACC breakdown →