OR4K2

Across TCGA patient cohorts, OR4K2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,705 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR4K2-associated GO terms across cancer lineages are Cellular senescence, Protein localization to vacuole, and RNA 3'-end processing. Each is linked with OR4K2 in more than 8 cancer types. Because this analysis shows association rather than direction, both OR4K2-to-partner and partner-to-OR4K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular senescence grouped by OR4K2-low versus OR4K2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K2→partner) and Y-score (partner→OR4K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular senescence →	+0.064	+0.211	<.001	<.001	3	9
STAD	Protein localization to vacuole →	+0.068	+0.201	<.001	<.001	3	9
ESCA	RNA 3'-end processing →	+0.082	+0.302	<.001	<.001	3	9
STAD	Blastocyst development →	+0.059	+0.195	<.001	<.001	3	9
STAD	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.057	+0.205	<.001	<.001	3	9
ESCA	Mitochondrial gene expression →	+0.078	+0.311	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,705 associations by consensus.

Cellular senescence by OR4K2 expression — STAD

Explore this box plot interactively →