OR4K2

Across TCGA cell cohorts, OR4K2 RNA expression is significantly associated with the mutation status of many other genes, with 129 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR4K2-associated genes across cancer lineages are USPL1, ESYT3, and RNF207. Each is linked with OR4K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4K2-to-partner and partner-to-OR4K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USPL1 grouped by OR4K2-low versus OR4K2-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K2→partner) and Y-score (partner→OR4K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	USPL1 →	+4.584	+0.075	.001	.003	3	1
BLOOD_Leukemia	ESYT3 →	+4.384	+0.025	.006	<.001	3	1
BLOOD_Leukemia	RNF207 →	+4.384	+0.025	.006	<.001	3	1
BLOOD_Leukemia	C1QC →	+5.969	+0.042	.001	<.001	3	1
BLOOD_Leukemia	MCM3AP →	+3.232	+0.015	.001	<.001	3	1
BLOOD_Leukemia	PDPN →	+3.969	+0.020	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 129 associations by consensus.

USPL1 by OR4K2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →