OR4K17

Across TCGA cell cohorts, OR4K17 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4K17-associated genes across cancer lineages are SCGB1C2, IL9, and C10orf53. Each is linked with OR4K17 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4K17-to-partner and partner-to-OR4K17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C2 grouped by OR4K17-low versus OR4K17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K17→partner) and Y-score (partner→OR4K17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SCGB1C2 →	+0.073	+4.415	<.001	.007	3	1
BREAST	IL9 →	+0.040	+4.781	<.001	.003	3	1
BLOOD_Lymphoma	C10orf53 →	+0.038	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR10G7 →	+0.020	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	DPPA5 →	+0.208	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OPN1MW3 →	+0.006	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SCGB1C2 by OR4K17 expression — LARGE_INTESTINE

Explore this box plot interactively →