OR4K17

Across TCGA cell cohorts, OR4K17 mutation is significantly associated with the mutation status of many other genes, with 673 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR4K17-associated genes across cancer lineages are URB2, GART, and XPO6. Each is linked with OR4K17 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4K17-to-partner and partner-to-OR4K17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, URB2 grouped by OR4K17-low versus OR4K17-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K17→partner) and Y-score (partner→OR4K17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	URB2 →	+3.187	+3.963	.001	.001	1	3
BREAST	GART →	+4.857	+4.297	.009	.009	1	3
BREAST	XPO6 →	+5.442	+5.442	<.001	<.001	1	3
SKIN	SYNJ2 →	+3.035	+3.321	.008	.008	1	3
SKIN	CADPS2 →	+3.450	+4.133	<.001	<.001	1	3
BLOOD_Leukemia	ANPEP →	+3.548	+3.845	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 673 associations by consensus.

URB2 by OR4K17 expression — SKIN

Explore this box plot interactively →