OR4K1

Across TCGA patient cohorts, OR4K1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,930 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR4K1-associated GO terms across cancer lineages are Macromolecule methylation, RNA polymerase II preinitiation complex assembly, and Anatomical structure maturation. Each is linked with OR4K1 in more than 7 cancer types. Because this analysis shows association rather than direction, both OR4K1-to-partner and partner-to-OR4K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by OR4K1-low versus OR4K1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K1→partner) and Y-score (partner→OR4K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Macromolecule methylation →	+0.087	+0.036	<.001	<.001	3	8
STAD	RNA polymerase II preinitiation complex assembly →	+0.091	+0.038	<.001	<.001	3	8
STAD	Anatomical structure maturation →	+0.048	+0.060	<.001	<.001	3	7
STAD	Protein targeting to membrane →	+0.094	+0.037	<.001	<.001	3	7
STAD	RNA 3'-end processing →	+0.097	+0.037	<.001	<.001	3	7
STAD	Protein methylation →	+0.083	+0.075	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,930 associations by consensus.

Macromolecule methylation by OR4K1 expression — STAD

Explore this box plot interactively →