OR4K1

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR4K1 RNA expression is significantly associated with the mutation status of many other genes, with 92 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4K1-associated genes across cancer lineages are ZNF668, PRR14L, and ZNF727. Each is linked with OR4K1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4K1-to-partner and partner-to-OR4K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF668 grouped by OR4K1-low versus OR4K1-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4K1→partner) and Y-score (partner→OR4K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEZNF668 →+4.977+0.015.002<.00132
SOFT_TISSUEPRR14L →+4.977+0.015.002<.00132
SOFT_TISSUEZNF727 →+5.977+0.020.001<.00132
SOFT_TISSUEPTPN21 →+5.977+0.020.001<.00132
OVARYPRAME →+5.196+0.029.005<.00132
LUNG_NSCLC_LUADPCDHA3 →+3.813+0.013.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 92 associations by consensus.

ZNF668 by OR4K1 expression — SOFT_TISSUE

Box plot of ZNF668 in OR4K1-low vs OR4K1-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration