Across TCGA pan-cancer cohorts, OR4F5 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated OR4F5 data layer compared with 7 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OR4F5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4F5 expression acts as an unfavorable survival marker.

HNSC are the cancer types where OR4F5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.176	0.685	.024	30	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: OR4F5 tumor-vs-normal RNA expression · all OR4F5 data types