OR4F4

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR4F4 RNA expression is significantly associated with the mutation status of many other genes, with 278 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4F4-associated genes across cancer lineages are JAG2, THOP1, and PXDN. Each is linked with OR4F4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4F4-to-partner and partner-to-OR4F4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JAG2 grouped by OR4F4-low versus OR4F4-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4F4→partner) and Y-score (partner→OR4F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaJAG2 →+3.169+0.006.008.00633
BLOOD_MyelomaTHOP1 →+4.754+0.045<.001.00232
BREASTPXDN →+4.196+0.028.006<.00132
LUNG_SCLCITPRID2 →+5.643+0.016.002<.00132
LUNG_SCLCGIGYF2 →+4.643+0.012.004<.00132
BLOOD_LymphomaAGAP1 →+3.584+0.009.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 278 associations by consensus.

JAG2 by OR4F4 expression — BLOOD_Lymphoma

Box plot of JAG2 in OR4F4-low vs OR4F4-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration