OR4D6

Across TCGA pan-cancer cohorts, OR4D6 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated OR4D6 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher OR4D6 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4D6 expression acts as an unfavorable survival marker.

BRCA and SKCM are the cancer types where OR4D6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	III,IV	0.207	0.833	<.001	18	view →
SKCM	OS	Median	All	0.132	0.326	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

OR4D6–BRCA (OS)

Open the BRCA breakdown →