OR4D6

Across TCGA patient cohorts, OR4D6 mutation is significantly associated with the RNA expression of many other genes, with 865 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4D6-associated genes across cancer lineages are RNA5SP339, LRRC59, and CEMIP2. Each is linked with OR4D6 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4D6-to-partner and partner-to-OR4D6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP339 grouped by OR4D6-low versus OR4D6-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D6→partner) and Y-score (partner→OR4D6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP339 →	+0.128	+3.081	<.001	.006	3	3
SKCM	LRRC59 →	+0.572	+3.604	.002	.001	3	3
UCEC	CEMIP2 →	+0.690	+2.928	.007	.001	3	3
GBM	MIR6856 →	+0.595	+5.149	<.001	.007	3	2
GBM	UGT1A6 →	+0.018	+5.352	<.001	.005	3	2
HNSC	RNU6-645P →	+0.335	+3.952	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 865 associations by consensus.

RNA5SP339 by OR4D6 expression — LUAD

Explore this box plot interactively →