OR4D6

Across TCGA cell cohorts, OR4D6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR4D6-associated genes across cancer lineages are SLC10A2, TPPP2, and CDR1. Each is linked with OR4D6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D6-to-partner and partner-to-OR4D6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC10A2 grouped by OR4D6-low versus OR4D6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D6→partner) and Y-score (partner→OR4D6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SLC10A2 →	+0.004	+4.437	<.001	.004	3	1
SKIN	TPPP2 →	+0.068	+4.217	<.001	.001	3	1
SKIN	CDR1 →	+0.194	+3.920	.002	.005	3	1
LARGE_INTESTINE	OR2M5 →	+0.016	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IQCF5 →	+0.037	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SLC10A2 by OR4D6 expression — SKIN

Explore this box plot interactively →