OR4D5

Across TCGA pan-cancer cohorts, OR4D5 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OR4D5 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher OR4D5 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4D5 expression acts as an unfavorable survival marker.

DLBC, SARC, and GBM are the cancer types where OR4D5 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	II,III,IV	0.118	0.802	.025	12	view →
SARC	OS	Median	All	0.147	0.594	.008	6	view →
GBM	DFS	Median	All	0.105	0.260	.024	6	view →
LIHC	DFS	Median	All	0.149	0.555	.024	6	view →
SKCM	OS	Median	IV	0.415	0.861	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OR4D5–DLBC (OS)

Open the DLBC breakdown →