OR4D5

Across TCGA patient cohorts, OR4D5 mutation is significantly associated with the RNA expression of many other genes, with 2,342 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4D5-associated genes across cancer lineages are MIR8076, SCD, and TMEM126A. Each is linked with OR4D5 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR4D5-to-partner and partner-to-OR4D5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8076 grouped by OR4D5-low versus OR4D5-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D5→partner) and Y-score (partner→OR4D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MIR8076 →	+0.540	+5.108	.001	.001	3	3
UCEC	SCD →	+0.925	+2.243	<.001	.005	3	3
LUAD	TMEM126A →	+0.484	+3.205	.003	.009	2	4
LUAD	RNU6-875P →	+0.855	+3.582	<.001	.003	3	3
UCEC	ZNHIT3 →	+0.401	+2.828	.003	<.001	3	3
UCEC	CCDC43 →	+0.401	+1.958	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,342 associations by consensus.

MIR8076 by OR4D5 expression — GBM

Explore this box plot interactively →