OR4D10

Across TCGA pan-cancer cohorts, OR4D10 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR4D10 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher OR4D10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4D10 expression acts as an unfavorable survival marker, although some lineages such as SCLC show a favorable association.

ESCA, SCLC, and SKCM are the cancer types where OR4D10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.130	0.703	<.001	24	view →
SCLC	OS	Median	III,IV	1.000	0.396	.016	12	view →
SKCM	DFS	Median	III,IV	0.174	0.659	.007	8	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUSC	OS	Median	III,IV	0.137	0.673	.002	6	view →
COAD	OS	Median	III,IV	0.161	0.780	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR4D10–ESCA (OS)

Open the ESCA breakdown →