OR4D10

Across TCGA cell cohorts, OR4D10 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4D10-associated genes across cancer lineages are SLC35G3, TBC1D21, and OR4F4. Each is linked with OR4D10 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D10-to-partner and partner-to-OR4D10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC35G3 grouped by OR4D10-low versus OR4D10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D10→partner) and Y-score (partner→OR4D10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC35G3 →	+0.011	+4.467	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR4F4 →	+0.017	+4.273	.001	.006	3	1
LARGE_INTESTINE	ELOA3DP →	+0.026	+4.273	<.001	.006	3	1
LARGE_INTESTINE	PFN3 →	+0.169	+4.467	<.001	.004	3	1
LARGE_INTESTINE	PYDC2 →	+0.108	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

SLC35G3 by OR4D10 expression — LARGE_INTESTINE

Explore this box plot interactively →