OR4D1

Across TCGA pan-cancer cohorts, OR4D1 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated OR4D1 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher OR4D1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR4D1 expression acts as an unfavorable survival marker.

OV, BLCA, and COAD are the cancer types where OR4D1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.007	0.844	<.001	48	view →
BLCA	OS	Median	III,IV	0.225	0.686	.002	24	view →
COAD	DFS	Median	All	0.198	0.693	<.001	22	view →
DLBC	DFS	Median	II,III,IV	0.022	0.837	<.001	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
HNSC	OS	Median	II,III,IV	0.222	0.710	.031	6	view →
SARC	DFS	Median	All	0.098	0.611	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

OR4D1–OV (OS)

Open the OV breakdown →