OR4D1

Across TCGA patient cohorts, OR4D1 mutation is significantly associated with the RNA expression of many other genes, with 1,231 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4D1-associated genes across cancer lineages are MIR4477A, OSBPL9P3, and MIR3939. Each is linked with OR4D1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4D1-to-partner and partner-to-OR4D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4477A grouped by OR4D1-low versus OR4D1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D1→partner) and Y-score (partner→OR4D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4477A →	+0.366	+1.926	.002	.001	3	3
SKCM	OSBPL9P3 →	+0.033	+2.595	<.001	<.001	3	2
SKCM	MIR3939 →	+0.327	+1.567	<.001	.009	3	2
SKCM	MIR4482 →	+0.945	+1.854	.006	.005	3	2
BLCA	CYP11B2 →	+0.013	+4.788	.004	.006	3	2
SKCM	BCCIP →	+0.446	+2.267	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,231 associations by consensus.

MIR4477A by OR4D1 expression — SKCM

Explore this box plot interactively →