OR4D1

Across TCGA patient cohorts, OR4D1 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4D1-associated genes across cancer lineages are INPP4B, JNK2, and mTOR_pS2448. Each is linked with OR4D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D1-to-partner and partner-to-OR4D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by OR4D1-low versus OR4D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D1→partner) and Y-score (partner→OR4D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.347	-3.700	.006	.001	3	2
UCEC	JNK2 →	+0.351	+3.169	<.001	<.001	3	2
UCEC	mTOR_pS2448 →	-0.149	-3.308	.011	.009	3	2
UCEC	PCNA →	+0.305	+2.502	<.001	.002	3	2
UCEC	4E-BP1 →	+0.391	+3.584	<.001	.002	3	2
UCEC	14-3-3_beta →	-0.083	-2.973	.034	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

INPP4B by OR4D1 expression — UCEC

Explore this box plot interactively →