OR4D1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR4D1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR4D1-associated genes across cancer lineages are FHL5 and INSL4. Each is linked with OR4D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D1-to-partner and partner-to-OR4D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FHL5 grouped by OR4D1-low versus OR4D1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D1→partner) and Y-score (partner→OR4D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINFHL5 →+0.132+5.000<.001<.00131
SKININSL4 →+0.534+3.791<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FHL5 by OR4D1 expression — SKIN

Box plot of FHL5 in OR4D1-low vs OR4D1-high samples in SKIN.

Explore this box plot interactively →

Exploration