OR4D1

Across TCGA cell cohorts, OR4D1 mutation is significantly associated with the mutation status of many other genes, with 485 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR4D1-associated genes across cancer lineages are CCDC178, KIF18B, and COL13A1. Each is linked with OR4D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4D1-to-partner and partner-to-OR4D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC178 grouped by OR4D1-low versus OR4D1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4D1→partner) and Y-score (partner→OR4D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CCDC178 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	KIF18B →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	COL13A1 →	+6.014	+6.014	.001	.001	1	2
STOMACH	CYP27B1 →	+4.807	+4.807	.008	.008	1	2
STOMACH	COL9A1 →	+4.807	+4.807	.008	.008	1	2
STOMACH	GRIA2 →	+4.807	+4.807	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 485 associations by consensus.

CCDC178 by OR4D1 expression — BLOOD_Lymphoma

Explore this box plot interactively →