OR4C4P

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR4C4P mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4C4P-associated genes across cancer lineages are ERK2, P-Cadherin, and ASNS. Each is linked with OR4C4P in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C4P-to-partner and partner-to-OR4C4P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C4P→partner) and Y-score (partner→OR4C4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECERK2 →+0.202+3.000.045.03631
UCECP-Cadherin →-0.200-3.308.007.01031
UCECASNS →+0.511+3.321.006.01031
UCECCaspase-7-cleavedD198 →+0.674+3.321.030.01031
UCECDi-Ras3 →-0.161-2.986.038.03531
UCECp53 →-0.409-3.000.044.03621
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration