Across TCGA cell cohorts, OR4C46 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OR4C46-associated genes across cancer lineages are KRTAP4-4, GABRA4, and TXNDC8. Each is linked with OR4C46 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C46-to-partner and partner-to-OR4C46 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C46→partner) and Y-score (partner→OR4C46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP4-4 →	+0.019	+4.058	<.001	.009	3	2
OESOPHAGUS	GABRA4 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	TXNDC8 →	+0.016	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	LIM2 →	+0.011	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	STATH →	+0.222	+3.947	<.001	.004	3	1
LUNG_NSCLC_LUAD	SCGB1C1 →	+0.043	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

OR4C46 survival (RNA) · tumor vs normal (RNA) · all OR4C46 data types